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>/S/Span/Pg 110 0 R/Type/StructElem/K<>>> 30<><

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>/S/Link/Pg 178 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-7)/K[<><>]/Alt(1986)>> 6]>><

>/S/P/Pg 178 0 R/Type/StructElem/K[<><

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>/S/Link/Pg 178 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-32)/K[<><>]/Alt(2015)>> 11]>><

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>/S/Link/Pg 178 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-6)/K[<><>]/Alt(1990)>> 19<

>/S/Link/Pg 178 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-34)/K[<><>]/Alt(2017)>> 21]>><

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>/S/Link/Pg 268 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-23)/K[<><>]/Alt(2018)>> 18]>><

>/S/P/Pg 268 0 R/Type/StructElem/K[<><

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>/S/P/Pg 303 0 R/Type/StructElem/K[<><

>/S/Span/Pg 303 0 R/Type/StructElem/K<>>> 13<>]>><

>/S/P/Pg 324 0 R/Type/StructElem/K[<><

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>/S/Link/Pg 324 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-19)/K[<><>]/Alt(2007b)>> 7]>><

>/S/P/Pg 324 0 R/Type/StructElem/K<>>><

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>/S/Link/Pg 324 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-25)/K[<><>]/Alt(2003)>> 15<

>/S/Link/Pg 324 0 R/Type/StructElem/ID(ref_oxfordhb-9780190947750-e-13-bibItem-30)/K[<><>]/Alt(2010)>> 17]>>]>>(oxfordhb-9780190947750-e-13-div1-8)<

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> endobj 2 0 obj <> endobj 828 0 obj <>stream application/pdfThe term “equipoise” refers to a state of uncertainty about the relative merits of a set of interventions, such as medical treatments for a particular disease or alternative policies for promoting economic, educational, or public health outcomes. This chapter discusses the role of equipoise in ensuring that research generates scientifically sound and socially valuable information while respecting the rights and welfare of the individuals whose interests are impacted by the conduct of the research. Alternative formulations of equipoise are distinguished, as are alternative ethical frameworks that provide a rationale for, and give content to, this appeal to uncertainty. It is argued that equipoise can be grounded in a general framework that applies to all research with humans that reconciles the imperative to produce socially valuable information with respect for the status of both participants and community members as free and equal persons.The term “equipoise” refers to a state of uncertainty about the relative merits of a set of interventions, such as medical treatments for a particular disease or alternative policies for promoting economic, educational, or public health outcomes. This chapter discusses the role of equipoise in ensuring that research generates scientifically sound and socially valuable information while respecting the rights and welfare of the individuals whose interests are impacted by the conduct of the research. Alternative formulations of equipoise are distinguished, as are alternative ethical frameworks that provide a rationale for, and give content to, this appeal to uncertainty. It is argued that equipoise can be grounded in a general framework that applies to all research with humans that reconciles the imperative to produce socially valuable information with respect for the status of both participants and community members as free and equal persons.Equipoise: Integrating Social Value and Equal Respect in Research with Humans - Oxford Handbooks RealObjects PDFreactor(R) 10.1.10722.5, Serial No: 3892, Licensed for: Oxford University Press 2021-01-13T15:55:56-05:002021-01-13T15:55:56-05:002021-01-13T15:55:56-05:00RealObjects PDFreactor(R) 10.1.10722.5, Serial No: 3892, Licensed for: Oxford University Press uuid:46d15a5c-d536-4b7f-8e4a-06f944af4ce01defaultuuid:b44ca891-d426-4130-965b-25b67b037c9c 1 endstream endobj 829 0 obj <>]/Names 796 0 R/Metadata 828 0 R/Type/Catalog/StructTreeRoot 2 0 R/Lang(en)/Outlines 734 0 R/MarkInfo<>/Pages 794 0 R/ViewerPreferences<>>> endobj 830 0 obj <> endobj xref 0 831 0000000000 65535 f 0000000015 00000 n 0000739842 00000 n 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